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Malignancy   Listen
noun
Malignancy, Malignance  n.  
1.
The state or quality of being malignant; extreme malevolence; bitter enmity; malice; disposition toward evil; intense ill will; as, malignancy of heart.
2.
Unfavorableness; evil nature. "The malignancy of my fate might perhaps distemner yours."
3.
(Med.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.
4.
Hence: (Med.) A cancerous tumor that is spreading beyond the point of origin.
Synonyms: malignant tumor, malignant neoplasm, metastatic tumor.
5.
The state of being a malignant.






Collaborative International Dictionary of English 0.48








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"Malignancy" Quotes from Famous Books



... such as this was the best antidote against affliction, whose arrows are never with so little difficulty repelled, as when they light upon a conscience which no self-reproach has laid bare to their malignancy. ...
— Cecilia vol. 2 - Memoirs of an Heiress • Frances (Fanny) Burney (Madame d'Arblay)

... tore his hair and his hat, and cursed and champed and howled. I sat holding his horse and feeling my satisfaction rise like the mercury in a warmed thermometer. Contrasting this mood with the cold malignancy and resolve of his temper in the soldiers' room at Sessions's, I saw, to my delight, that our secret was forever imprisoned in his breast, gagged and chained down by the iron of his own inextricable infamy. At dawn he awakened me that he might persuade me to reject the evidences ...
— The Cavalier • George Washington Cable

... alluded to is a new tale, devised in the malignancy of party, has been asserted by you; and on this assertion is founded many of your strongest conclusions in favour of your own innocence. But what must the world think of your effrontery, when they read the following letter of Col. Alexander Hamilton, who was then Aid-de-Camp to the ...
— Nuts for Future Historians to Crack • Various

... permitted to assemble in safety at the seat of Government for the discharge of our important duties. But when we reflect that this fatal disorder has within a few years made repeated ravages in some of our principal sea ports, and with increased malignancy, and when we consider the magnitude of the evils arising from the interruption of public and private business, whereby the national interests are deeply affected, I think it my duty to invite the Legislature of the Union to examine the expediency of ...
— State of the Union Addresses of John Adams • John Adams

... Malignancy was rampant and Arnold was pursued with great bitterness. Joseph Reed, the President of the Executive Council of Pennsylvania, not only brought charge against him of abusing his position for his own advantage, but also laid the charges before each State government. ...
— Washington and his Comrades in Arms - A Chronicle of the War of Independence • George Wrong

... overwhelming preponderance of evidence from numerous authentic sources pointed to the tenacious existence of certain forces of great power and, so far as the human point of view is concerned, exceptional malignancy. To say that we actually believed in vampires or werewolves would be a carelessly inclusive statement. Rather must it be said that we were not prepared to deny the possibility of certain unfamiliar and unclassified modifications of vital force and attenuated matter; existing ...
— The Shunned House • Howard Phillips Lovecraft

... the conference, seemed agitated by a variety of emotions. He soon, however, recovered his composure, and an expression of determined malignancy settled upon his countenance, as he gave peremptory orders that a certain chamber should be immediately locked up, and the key ...
— The Works of Edgar Allan Poe - Volume 4 (of 5) of the Raven Edition • Edgar Allan Poe

... on a new plan. His offers were accepted, and he was clothed with full powers. He was a man of talent and enterprise, and a violent enemy to foreigners. The missionaries feared everything from his malignancy; and their fears were ...
— Lives of the Three Mrs. Judsons • Arabella W. Stuart

... peculiar manner, and very disagreeably; and a thick, waxy complexion, worse in childhood than of late years, for the spirit had not then found its way through it, as it did afterward. Moreover, by a singular malignancy of fortune, when she was twelve years old, she was attacked with varioloid, and taking a severe cold as she was getting well, had a relapse, and was left as you see her, not closely marked, but sufficiently pitted ...
— The Continental Monthly, Vol. III, No. V, May, 1863 - Devoted to Literature and National Policy • Various

... rise and in front of us rose the huge expanse of the moor, mottled with gnarled and craggy cairns and tors. A cold wind swept down from it and set us shivering. Somewhere there, on that desolate plain, was lurking this fiendish man, hiding in a burrow like a wild beast, his heart full of malignancy against the whole race which had cast him out. It needed but this to complete the grim suggestiveness of the barren waste, the chilling wind, and the darkling sky. Even Baskerville fell silent and pulled his ...
— The Hound of the Baskervilles • A. Conan Doyle

... were sincerely attached to him; and the best established fortune would have been ruined at some period by a jest much less severe: for it was delivered in the presence of witnesses, who were only desirous of having an opportunity of representing it in its utmost malignancy, to make a merit of their vigilance with a powerful and absolute minister. Of this the Chevalier de Grammont was thoroughly convinced; yet whatever detriment he foresaw might arise from it, he could not help being much pleased with what he ...
— Marguerite de Navarre - Memoirs of Marguerite de Valois Queen of Navarre • Marguerite de Navarre

... tenement house, many school children are endangered, and the most perfect plumbing in a house affords little protection against the entrance of this disease, if it is prevailing in the vicinity. Typhus and smallpox do not confine their ravages to the vicious and foul, after they have acquired malignancy amongst them. Mingled with those who might not be worth saving, is a much larger number of honest, industrious, and fairly intelligent and energetic poor people who live by days' wages, and are struggling against their surroundings ...
— White Slaves • Louis A Banks

... from the society of men, and most of all from that of Englishmen. The more beautiful and genial inspirations of his muse were looked upon but as lucid intervals between the paroxysms of an inherent malignancy of nature. But how totally all this differed from the Byron of the social hour, they who lived in familiar intercourse with him may be safely left to tell. As it was, no English gentleman ever approached him with the common forms of introduction, ...
— Beacon Lights of History, Volume XIII • John Lord

... both of his reckless contempt for public opinion and the malignancy with which he was misjudged, it could be found in an incident which took place towards the end of 1894. A journal entitled The Chameleon was produced by some Oxford undergraduates. Oscar wrote for it a handful of sayings which he called ...
— Oscar Wilde, Volume 1 (of 2) - His Life and Confessions • Frank Harris

... true) is of a menacing aspect, but if the new parliament (for whose convention so many good men pray) continue long to sit, I fear not but the star will lose its virulence and malignancy, or at least its portent be averted from this our nation; which being the humble request to God of all good men, makes me thus entitle ...
— A Budget of Paradoxes, Volume I (of II) • Augustus De Morgan

... baby. I tell you it was sheer Providence that I didn't drop that lamp and set the whole place alight. The head on the pillow turned and I saw a face looking up at me which seemed to me to have more malignancy and wickedness than ever I had dreamed of in a nightmare. It was the flush of red over the cheekbones, and the brooding eyes full of loathing of me, and of everything else, that impressed me. I'll never ...
— Round the Red Lamp - Being Facts and Fancies of Medical Life • Arthur Conan Doyle

... whereto their youngest sister had risen, and the magnificence of her marriage-festival, their hearts were fired with envy and jealousy and sore despite and they resolved upon giving the rein to their hatred and malignancy and to work her some foul mischief. On this wise they remained for many months consumed with rancour, day and night; and they burned with grief and anger whenever they sighted aught of her superior style and state. One morning ...
— Supplemental Nights, Volume 3 • Richard F. Burton

... Macphail watched the rain. It was beginning to get on his nerves. It was not like our soft English rain that drops gently on the earth; it was unmerciful and somehow terrible; you felt in it the malignancy of the primitive powers of nature. It did not pour, it flowed. It was like a deluge from heaven, and it rattled on the roof of corrugated iron with a steady persistence that was maddening. It seemed to have a fury of its own. And sometimes ...
— The Trembling of a Leaf - Little Stories of the South Sea Islands • William Somerset Maugham

... said, and he or his tools could have had any influence, the words if provd, would have been adjudgd to have been said in sober earnest, and would have been considered as material to have shown the malignancy of the heart. ...
— The Writings of Samuel Adams, volume II (1770 - 1773) - collected and edited by Harry Alonso Cushing • Samuel Adams

... emeralds, glared down into the face of the man with such intense malignancy that they seemed to stream forth a cold evil light. Fortunately he was paralyzed with fright. The slightest movement would have caused that fanged maw to lash down into ...
— Out of the Depths - A Romance of Reclamation • Robert Ames Bennet

... "As the degrees of malignancy vary in people according as they have more or less of the Old Serpent (the father of hisses) in their composition, I have sometimes amused myself with analyzing this many-headed hydra, which calls itself the public, into the component parts of which it is 'complicated, head and tail,' ...
— Atlantic Monthly, Volume 11, Issue 67, May, 1863 • Various

... and wainscot, &c. the fancerings (as they term it) and mouldings; since beside the everlastingness of the wood, enemy to worms, and those other corruption we have named, it would likewise greatly cure and reform the malignancy and ...
— Sylva, Vol. 1 (of 2) - Or A Discourse of Forest Trees • John Evelyn

... settlement of religion, made in 1690, had revived and ratified the authority of our reforming parliaments, and laws made by them; then, as these obliged the king to swear the covenants before his coronation, and all ranks to swear them, and obliged to root out malignancy, sectarianism, &c., and to promote uniformity in doctrine, worship, discipline and government, in the three nations, so the revolution settlement would have obliged all to the practice of the same duties, and that, before ever king, or any under him, could ...
— Act, Declaration, & Testimony for the Whole of our Covenanted Reformation, as Attained to, and Established in Britain and Ireland; Particularly Betwixt the Years 1638 and 1649, Inclusive • The Reformed Presbytery

... infestation; epidemic, pandemic, endemic, epizootic; murrain, plague, pestilence, pox. sore, ulcer, abscess, fester, boil; pimple, wen &c. (swelling) 250; carbuncle, gathering, imposthume[obs3], peccant humor, issue; rot, canker, cold sore, fever sore; cancer, carcinoma, leukemia, neoplastic disease, malignancy, tumor; caries, mortification, corruption, gangrene, sphacelus[obs3], sphacelation[obs3], leprosy; eruption, rash, breaking out. fever, temperature, calenture[obs3]; inflammation. ague, angina pectoris[Lat], appendicitis; ...
— Roget's Thesaurus

... in battle. Upon this resolution I procured a pass to go for Genoa, and accordingly began my journey, but was arrested at Villa Franca by a slow lingering fever, which held me about five days, and then turned to a burning malignancy, and at last to the plague. My friend, the captain, never left me night nor day; and though for four days more I knew nobody, nor was capable of so much as thinking of myself, yet it pleased God that the distemper gathered ...
— Memoirs of a Cavalier • Daniel Defoe

... his life occurred in the year 1793. In that year the yellow fever broke out with great malignancy in Philadelphia, and raged violently for about one hundred days, from about the last of July until the first of November. Nothing seemed capable of checking it. The people fled in dismay from their homes, and the city seemed given over to desolation. In the terrible "hundred ...
— Great Fortunes, and How They Were Made • James D. McCabe, Jr.

... it could not be Providence, whose favourite he had ever been. We must have a couple of Powers to account for discomfort when Egoism is the kernel of our religion. Benevolence had singled him for uncommon benefits: malignancy was at work to rob him of them. And you think well of the ...
— The Shaving of Shagpat • George Meredith

... the degree of genius.—A perpetual fever among authors and artists. —Instances of its incredible excess among brothers and benefactors.—Of a peculiar species, where the fever consumes the sufferer without its malignancy. 154 ...
— Literary Character of Men of Genius - Drawn from Their Own Feelings and Confessions • Isaac D'Israeli

... patience, no; my stars shine darkly over me; the malignancy of my fate might, perhaps, distemper yours; therefore I shall crave of you your leave that I may bear my evils alone. It were a bad recompense for your love, to lay ...
— Twelfth Night; or, What You Will • William Shakespeare [Collins edition]

... horrible clamour of the devils, and the despairing yells of the victims. The general effect is of one simultaneous convulsed movement, one seething turmoil. In detail, the horror is most dramatically rendered. The malignancy of the devils, their brutal fury as they claw their prey, tear at their throats, and wrench back their heads; the utter horror and anguish of the victims, the confusion, the uproar, are given with a convincing realistic ...
— Luca Signorelli • Maud Cruttwell

... were knocked on the head with a club, or shot with an arrow, the cause of death is clearly the malignancy of the person using these weapons; and so it is easy to think that a man killed by a fallen tree, or by the upsetting of a canoe in the surf, or in an eddy in the river, is also the victim of some being using these things ...
— Travels in West Africa • Mary H. Kingsley

... more shew the malignancy of his character than in his attacks on Johnson's black servant, and through him on Johnson. With the passage in which this offensive caveat is found he brings his work to a close. At the first mention of Frank ...
— Life Of Johnson, Volume 4 (of 6) • Boswell

... during the early period of camp life, when they were just foregoing their old habits and were not yet hardened to the new, or it may be that when men are congregated in great numbers, certain diseases, by transmission from one to another, may be cultivated into extraordinary malignancy—at any rate a large proportion of the inmates of every camp sickened and many died. At Bowlinggreen in the winter of 1861 and 1862, the mortality was dreadful, measles, typhoid fever, pneumonia and diseases of the bowels, carried off a host of victims—every ...
— History of Morgan's Cavalry • Basil W. Duke

... that was just a whimper. Oh, irony of fate! Oh, cynicism incredible in its malignancy! Oh, cumulative touch! To deliver him this his enemy to strike, and to present him for the ...
— If Winter Comes • A.S.M. Hutchinson

... wondered what he could have been doing in that interminable interval. Then, reluctant but horribly fascinated, his look went back to the upturned, dreadful face. The malignancy had gone out of it. The eyes rolled no longer, but gazed with a great fixity at something that seemed to be infinitely far away. As Tommy looked, a terrible rattling breath went through the heavy, ...
— The Lamp in the Desert • Ethel M. Dell

... was almost at his elbow, leaning against a small table, rolling his tongue under his teeth. The eyes of the two men met, and under the bushy brows of Monkey Mack there was a reddish gleam in which the Honourable Walter Ryder read a baboon-like malignancy, and in a moment the latter realized that in all his plans and precautions he had never made due allowance for the cunning and depth of this extraordinary man; but his face ...
— In the Roaring Fifties • Edward Dyson

... into the black vacuum of the screen, blinking in the glaring lights, cowering instinctively before the unseen but certain malignancy of the power ...
— The Voice on the Wire • Eustace Hale Ball

... the fall of the temperature with increased jaundice and vomiting of dark altered blood, the "black vomit." Hemorrhages may also occur into the skin or mucous membranes. Brain symptoms are sometimes severe. Convalescence is usually gradual. The disease varies from great mildness to extreme malignancy. Mortality from fifteen to eighty-five ...
— Mother's Remedies - Over One Thousand Tried and Tested Remedies from Mothers - of the United States and Canada • T. J. Ritter

... him into captivity. Well might he "protest in the face of Heaven and mankind against the violence that was being enacted" towards him. Well might he appeal to history to avenge him. There is nothing in history to equal the malignancy of the conquerors' treatment of their fallen foe. We shall see now and hereafter prejudices making way, reluctantly it may be, but surely, for the justice that ...
— The Tragedy of St. Helena • Walter Runciman

... as "Snarling" Van Gilbert. His important part was played in drafting the new code after the Chicago Commune. But before that, as trial judge, he had earned sentence of death by his fiendish malignancy. I was one of those that tried him and passed sentence upon him. Anna Roylston carried ...
— The Iron Heel • Jack London

... Burke has been mistaken and disappointed in the opinions he had formed of the affairs of France; but such is the ingenuity of his hope, or the malignancy of his despair, that it furnishes him with new pretences to go on. There was a time when it was impossible to make Mr. Burke believe there would be any Revolution in France. His opinion then was, that the French had ...
— The Writings Of Thomas Paine, Complete - With Index to Volumes I - IV • Thomas Paine

... because of the overstimulation that has been going on so long, there is a greatly enfeebled circulation and deposits are taking place. The tumor in the breast becomes cancerous; the scar in the womb takes on malignancy; the arteries harden; the circulation in the spinal cord becomes so impaired that induration is induced followed by ataxia; and other troubles of a like character could be mentioned. These are the most favorable results for, while these cases are winding their weary, sluggish ...
— Appendicitis: The Etiology, Hygenic and Dietetic Treatment • John H. Tilden, M.D.

... of John Keats. He stood in awe of his own artistic and poetic sense. He could say with truth that his own domestic criticism had given him pain without comparison beyond what Blackwood or the Quarterly could possibly inflict. If he had had any terrible heart-burning over their malignancy, if he had felt that his life was poisoned, he could hardly have forborne some allusion to it in his letters to his brother, George Keats. But he is almost imperturbable. He talks of the episode freely, says that he has been urged to publish his Pot of Basil as a reply to the ...
— The Bibliotaph - and Other People • Leon H. Vincent

... the considerable physicians, by their outward demeanour, seemed to be unbelievers; but at the same time, they everywhere insinuated, that there might be a pestilential malignancy in the air, occasioned by the comet, which might be armed against by proper and timely medicines. This caution had but little effect; for as the time approached, the Christian resignation of the people increased, and most of them (which was never before known) had their ...
— The Prose Works of Jonathan Swift, D. D., Volume IV: - Swift's Writings on Religion and the Church, Volume II • Jonathan Swift

... on the curtain—it had gone down in the old crooked lines—again looked above and beyond them all. I have sometimes fancied a trace of malignancy about her steady eyeballs, but perhaps that is the accident or the design of the scene-painter; it does not show in photographs. The audience was dispersing a trifle sedately; the performance had been, as Mrs. Barberry told Mr. Justice Horne, interesting ...
— The Path of a Star • Mrs. Everard Cotes (AKA Sara Jeannette Duncan)

... the meantime, to see a cessation of the abuses of public officers and of almost every measure of government with which some of the gazettes are so strongly impregnated, and which cannot fail, if persevered in with the malignancy with which they now teem, of rendering the Union asunder. The seeds of discontent, distrust, and irritation which are so plentifully sown, can scarcely fail to produce this effect, and to mar that prospect of happiness which, perhaps, never beamed with more ...
— Life And Times Of Washington, Volume 2 • John Frederick Schroeder and Benson John Lossing

... inconsiderable rhymester in Petticoat Lane, it made no difference; there was no crime too heinous for "the great Mr. Pope's" next verses to charge you with, and, worst of all, there was no misdoing so out of character that his adroit malignancy could not ...
— The Certain Hour • James Branch Cabell

... expression that no chaste female might endure. While she was shrinking within herself, in dread of having her ears wounded by some proposal still more shocking than the last, the voice of Magua answered, in its tones of deepest malignancy: ...
— The Last of the Mohicans • James Fenimore Cooper

... trade with the West India Islands, which had been the mainstay of their prosperity in colonial times; and after the British Government, in 1783, restricted that trade to British vessels, many people in the United States were attributing hard times to British malignancy. The only action which seemed possible was to force Great Britain in particular, but other foreign countries as well, to make such trade agreements as the prosperity of the United States demanded. The only hope seemed to lie in a commercial ...
— The Fathers of the Constitution - Volume 13 in The Chronicles Of America Series • Max Farrand

... mesmerism. The Italians, especially the Neapolitans, very generally wear amulets. Pio Nono, perhaps as being the chief of all monks and other religious people, is supposed to have an evil eye of tenfold malignancy; and its effect has been seen in the ruin of all schemes for the public good so soon as they are favored by him. When the pillar in the Piazza de' Spagna, commemorative of his dogma of the Immaculate Conception, was ...
— Passages From the French and Italian Notebooks, Complete • Nathaniel Hawthorne

... horribly and perhaps when less prepared for it than now. And you, my darling, my imperial one! you would not escape. Besides, you have forgotten the young man who, with such unselfishness, has lent himself to your schemes in my favor. What could save him if I disappointed the malignancy of Madame. No; I have destroyed others, and must submit to the penalty incurred by murder. Kiss me, Irene, and go. I ...
— The Bronze Hand - 1897 • Anna Katharine Green (Mrs. Charles Rohlfs)

... boa-constrictor. In poetry the characteristic most often attributed to a snake is malignancy. But in this picture of the serpent lying dormant and waiting for the sloughing of its old skin in the springtime, when it will come forth with new beauty and power, the idea presented is that of ...
— Selections from the Poems and Plays of Robert Browning • Robert Browning

... his eyes were devilish. "You had better come without further trouble," he remarked. "You will only add to your punishment—which will be no light one as it is—by these hysterics. Do you wish to see my proofs?" He addressed Merryon with sudden open malignancy. "Or am I to take them to the ...
— The Safety Curtain, and Other Stories • Ethel M. Dell

... them as they are; and go to Caracas; if I do not find myself well received there, I will go to Buenos Ayres; I will go to California; in fine, I will go from shore to shore, till I meet with an asylum against the malignancy and persecutions of men."—"Supposing your Majesty to speak seriously, can you reasonably flatter yourself with continually escaping the snares and fleets of the English?"—"If I cannot escape them, they will ...
— Memoirs of the Private Life, Return, and Reign of Napoleon in 1815, Vol. II • Pierre Antoine Edouard Fleury de Chaboulon

... all, the pitch of glaring hatred with which the man eyed me and addressed me, were most unpleasant. I swear I knew fear—not calculated caution, not timid apprehension, but blind, panic, unreasoned terror. The malignancy of the creature was blood curdling; nor did it require words to convey it: it poured from him, out of his red-rimmed, blazing eyes, out of his withered, twisted, tortured face, out of his broken-nailed, crooked ...
— The Mutiny of the Elsinore • Jack London

... to mention here, had only just missed succeeding in the passing of Bar Exam owing to the inveterate malignancy of his stars and lack of a more industrial temperament; but from the coolness of his cheek, and complete man-of-the-worldliness, is a most judicious and tip-top adviser to friends in ...
— Baboo Jabberjee, B.A. • F. Anstey

... considered it his duty to treat us as animals and to shout rudely and insolently: "Wait! Don't you come pushing your way in here!" Even the dogs, even they were hostile to us and hurled themselves at us with a peculiar malignancy. But what struck me most of all in my new position was the entire lack of justice, what the people call "forgetting God." Rarely a day went by without some swindle. The shopkeeper, who sold us oil, the contractor, the workmen, the customers themselves, all cheated. ...
— The House with the Mezzanine and Other Stories • Anton Tchekoff

... apprentices resisted the interference of the lord mayor and his officers who would have put a stop to their decorating a pump in Cornhill with evergreens at Christmas, and not only did ministers who had been deprived for malignancy occupy pulpits in various city churches on that day, but they used ...
— London and the Kingdom - Volume II • Reginald R. Sharpe

... of reason and in the light of truth. And you, who were my one professed friend, the one man who spoke so loudly of dying in my service, you falsified my vision, you masked him—either at his own and at my brother's bidding, or else out of the malignancy of your nature—in a garb that should render him agreeable in my eyes. Do you realise what you have done? Does not your conscience tell you? You have contrived that I have plighted my troth to a man such as I believed ...
— The Shame of Motley • Raphael Sabatini

... of the charitable or civic organizations which he officially headed. Thus he shone forth as a useful, serviceable, and public-spirited citizen, against whom (such was the inference which the newspaper reader was expected to draw) only malignancy could allege anything injurious. In this instance his offering upon the altar of publicity, carefully typed and mimeographed, had just enough importance to entitle it to a paragraph of courtesy. After it was given out to those who ...
— Success - A Novel • Samuel Hopkins Adams



Words linked to "Malignancy" :   malignant, malignity, malignant tumor, malignant neoplasm, disease, malignance, evil, malign, benignancy, cancer cell, metastatic tumor



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